A correlation between fraternal birth order and sexual orientation has been suggested by recent research. Referred to in psychology as the fraternal birth order effect, the observation is that the more older brothers a man has, the greater the probability is that he will have a homosexual sexual orientation.
The fraternal birth order effect is the strongest known predictor of sexual orientation; according to various studies, each older brother increases a man's chances of developing a homosexual sexual orientation by from 28% to 48%. The fraternal birth order effect accounts for approximately one seventh of the prevalence of homosexuality in men. There seems to be no effect on sexual orientation in women, and no effect related to the number of older sisters.
Large studies involving adoptees demonstrate that the effect is not due to being raised with older brothers, but appears to have something to do with changes induced in the uterus when gestating a boy that affects subsequent sons. The effect is present regardless of whether or not the older brothers are raised in the same family environment with the boy. There is no effect when the number of older brothers is increased by adopted brothers or step brothers. It is hypothesized that the fraternal birth order effect may be caused by increasing levels of antibodies produced by the mother to the histocompatibility Y-antigen with each son. The HY antigen is found on the surface of the cells of male, but not female mammals. The presence of this foreign protein when bearing a son could trigger the mother's immune response, which may then lead to different brain development patterns in later male children.
The fraternal birth order effect appears to have the opposite effect in right-handed individuals than non-right-handed individuals, however the incidence of homosexuality correlated with an increase in older brothers is seen only in right handed males.
This article is based on "Fraternal birth order and sexual orientation" from the free encyclopedia Wikipedia (http://en.wikipedia.org). It is licensed under the terms of the GNU Free Documentation Licencse. In the Wikipedia you can find a list of the authors by visiting the following address: http://en.wikipedia.org/w/index.php?title=Fraternal+birth+order+and+sexual+orientation&action=history